UBC PiMS Research Group
Pharmacoepidemiology in Multiple Sclerosis Research Group


Genetic marker for drug risk in multiple sclerosis offers path toward precision medicine

via: Centreforbrainhealth.ca A team of researchers has uncovered a specific gene variant associated with an adverse drug reaction resulting in liver injury in a people with multiple sclerosis (MS). It is the first time researchers have been able to establish a validated genetic marker for a drug-induced harm in people with MS. Published today in […]

A constellation of symptoms presages first definitive signs of multiple sclerosis

Jose MA Wijandnd’s study ‘Five years before multiple sclerosis onset: Phenotyping the prodrome’ is now published in MSJ.

New Article: Sun exposure over the life course and associations with multiple sclerosis

Neurology has recently published Helen Tremlett’s article Sun exposure over the life course and associations with multiple sclerosis.

PiMS research featured in the Chronicle of Neurology & Psychiatry

Helen Tremlett’s ECTRIMS-ACTRIMS presentation was featured in the December 2017 issue of The Chronicle of Neurology & Psychiatry. Please find the coverage on pages 10 and 11 here.  


Meet José–cycling enthusiast hoping to improve the prognosis of people living with Multiple Sclerosis.

New article published in The Lancet Neurology

PiMS member José M A Wijnands article, “Health-care use before a first demyelinating event suggestive of a multiple sclerosis prodrome: a matched cohort study” was recently published in Lancet Neurology.

What’s new for ‘microbiota multiple sclerosis’ in PubMed

Helen Tremlett’s new article, “The gut microbiome in human neurological disease: A review”, was recently published in Annals of Neurology.

Association between anti-depressants drugs on the progression of multiple sclerosis.

Researchers found no evidence to suggest that exposure to the antidepressants ‘selective serotonin reuptake inhibitors’ were associated with a delay in MS disability accumulation or progression.

Unique Relationship Found Between Gut Microbiota and Immune Markers in Kids with MS

Children with multiple sclerosis (MS) may show a disruption in the balance of bacteria in the gut as early as two years into the disease course, suggests new findings from Dr. Helen Tremlett.

Associations between the gut microbiota and host immune markers in pediatric multiple sclerosis and controls

Dr. Helen Tremlett’s latest article has been published in BMC Neurology.

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